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Science / Hygiene / Undergraduate / syd50

Hygiene: Account for Clustered Study Data

Estimate a simple design effect for fictional classroom-level research.

All worksheets
5 questions0m 0s

Prerequisites

Study design, intraclass correlation, variance, sampling and human-participant research ethics.

Learn the skill

For equal cluster size m and intraclass correlation rho, a common planning approximation is DE = 1 + (m - 1)rho. Approximate effective sample size is n/DE. This is not a full analysis plan; few clusters, unequal sizes, missingness and estimand choice require more care.

Worked example

With 196 fictional participants in equal clusters of 28 and rho = 1/27, DE = 2 and approximate effective size is 98. Shared conditions within classes mean participants are not 196 independent replications of classroom assignment.

A fictional study assigns entire classrooms to a support program or comparison group. Students within each classroom share conditions, so analysis must account for clustering and provide supplies to everyone.
A fictional study assigns entire classrooms to a support program or comparison group. Students within each classroom share conditions, so analysis must account for clustering and provide supplies to everyone.
Question 1 What is DE in the example?
Question 2 What is the approximate effective sample size?
Question 3 How many clusters are represented by 196 participants in groups of 28?
Question 4 Does the effective-size shortcut solve small-cluster inference?
Question 5 What is a key ethics requirement for a support study?

Further inquiry

Derive the equal-cluster planning design effect from the variance of a mean under a common within-cluster correlation. Discuss unequal cluster sizes, a small number of randomized classes, and what an appropriate inferential plan would need. Use only fictional data and preserve access to essential supplies in any proposed design.

Review criteria

  • State the equal-size and correlation assumptions instead of treating the shortcut as universal.
  • Identify the unit of assignment separately from the participant count.
  • Explain uncertainty, safeguarding and privacy limits without collecting personal hygiene records.