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For a polynomial term ax^n, the derivative is a times n times x^(n-1). Differentiate each term, then substitute the requested input. A derivative gives a local rate, not the function's original value.
Worked example
For f(x) = x^3 + 2x, f'(x) = 3x^2 + 2. At x = 2, the tangent slope is 3 x 4 + 2 = 14.